Curate Reference PTDBDOC00033

---

Journal*

Year*

Volume*

Issue

First page*

Last page*

PUBMED ID

DOI

Title*

Authors*

Kang Zhou, Xia Yu, Xiulan Xie, and Shu-Ming Li

Abstract

Flavonoids are found mainly in plants and exhibit diverse biological and pharmacological activities, which can often be enhanced by prenylations. In plants, such reactions are catalyzed by membrane-bound prenyltransferases. In this study, the prenylation of nine flavonoids from different classes by a soluble fungal prenyltransferase (AnaPT) involved in the biosynthesis of the prenylated indole alkaloid acetylaszonalenin is demonstrated. The behavior of AnaPT toward flavonoids regarding substrate acceptance and prenylation positions clearly differs from that of the indole prenyltransferase 7-DMATS. The two enzymes are therefore complementary in flavonoid prenylations.

Type*

Article Review Personal communication Book