Curate Reference PTDBDOC00025

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Xia Yua, Aigang Yangb, Wenhan Linb, Shu-Ming Li

Abstract

Prenylated indolocarbazoles have been reported neither from natural sources, nor by chemical synthetic approaches. In this Letter, we report a regiospecific prenylation of indolocarbazoles at the para-position of the indole N-atom by two recombinant enzymes from the dimethylallyltryptophan synthase (DMATS) superfamily, that is, 5-DMATS from Aspergillus clavatus and FgaPT2 from Aspergillus fumigatus.

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Article Review Personal communication Book